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Imipramine 25mg


Imipramine 25mg is used for the treatment of persistent mental depression. It can be also used as a part of combination treatment for decreasing the rate of enuresis (incontinence) in children over the age of 5 and adults. This medication is used only in the cases of incontinence, when the patients don’t have any gallbladder disorders.

Pack Size PriceQuantity
100 Tablet/s $170.00
200 Tablet/s $300.00
500 Tablet/s $600.00
1000 Tablet/s $1,000.00


Imipramine 25mg falls within the group of drugs referred to as imipramines. The medicine is regarded as a tricyclic antidepressant and comes in the form of oral pills. The medicine also belongs to the group of benzodiazepines. The inactive components of Tofranil include cellulose compounds, sodium starch glycolate, calcium phosphate, talc, sucrose, povidone, docusate sodium, magnesium stearate, iron oxides, titanium dioxide, and polyethylene glycol.


Imipramine 25mg is used for the treatment of persistent mental depression. It can be also used as a part of combination treatment for decreasing the rate of enuresis (incontinence) in children over the age of 5 and adults. This medication is used only in the cases of incontinence when the patients don’t have any gallbladder disorders.


Common dosage advice

Doctors usually prescribe a low dosage (75 mg) of the medicine in the initial stage of the treatment. Later on, the dose may be gradually to about 200 mg a day. Take the drug with a full glass of water. Avoid chewing or crushing the pills, as it can reduce the effectiveness of the medication. In some people, the use of this drug may cause indigestion. In this case, you should take the drug with food or milk. Kids with incontinence should take a lower dosage. Elderly patients may require a higher dosage depending on the severity of their disease. Always follow the doctor’s prescriptions. Avoid changing the dose or stopping the treatment without the doctor’s approval.

Skipping the dose

If you missed the dose, you must take it as soon as possible. But it’s already time for the next dose, forget about the skipped one and keep following your common schedule. Avoid increasing the dose to compensate for the skipped one.


Overdose of this drug may be fatal. Therefore, you should never exceed the prescribed dosage. The signs of overdose are blackouts, cramps, sleepiness, sickness, blurred vision or even coma. In case of overdose, you should call the emergency at once.

Adverse effects

Most people have some adverse effects every time they start the new treatment. Nevertheless, it is essential to observe the adverse effects for frequency and severity and you should inform your physician if these symptoms get worse. The use of Imipramine 25mg may cause the following adverse effects:

Urination problems
Sores in the mouth
Head pain
Sudden weight change
Increased photosensitivity
Dry eyes
Decreased sexual desire
Hair loss
Swollen breast or nipple discharge
Sleeping disorders
Swollen glands
Severe abdominal pain
Lack of balance
Increased heart rate
Muscle cramps
Excessive hemorrhage

Drug interactions

Drug interactions may affect the way the act and reduce their effectiveness. In some cases, they may prove to be toxic to the organism. Therefore, it is essential to ask your doctor any questions you have about this drug. It is important to inform your physician if you’re using any herbal supplements, weight loss pills and over-the-counter drugs. Some medicines interacting with Tofranil are:

Valproic acid
Belladonna alkaloids


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