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1. Buy Natdac 30mg Online
Daclatasvir (Natdac) is the first-in-class NS5A inhibitor used in combination with Sofosbuvir for the treatment of patients with chronic hepatitis C virus (HCV) genotype 3 infection. Compared to other treatment options, this combination not only increases the cure rate but is also regarded as a valuable treatment option in some of the difficult-to-treat HCV patient subsets.
U.S. Food and Drug Administration approved Natdac 30mg(Daclatasvir) for use with sofosbuvir to treat hepatitis C virus (HCV) genotype 3 infections on July 24, 2015. NATDAC (Daclatasvir) is the first drug that has demonstrated safety and efficacy to treat genotype 3 HCV infections without the need for co-administration of interferon or ribavirin, two FDA-approved drugs also used to treat HCV infection.
2. How To Natdac 30mg Work?
Daclatasvir prevents RNA replication and virion assembly by binding to NS5A, a nonstructural phosphoprotein encoded by HCV. Binding to the N-terminus of the D1 domain of NS5A prevents its interaction with host cell proteins and membranes required for virion replication complex assembly.
Daclatasvir must be used in combination with other medicines that attack the hepatitis C virus in different ways. If daclatasvir is used on its own there is a high chance that the hepatitis C virus will become resistant to it.
3. What is Natdac 30mg Tablet?
Natdac (Daclatasvir) is an antiviral medicine that prevents the hepatitis C virus (HCV) from multiplying in your body. Natdac is used to treat genotype 1 and genotype 3 chronic hepatitis C in adults with or without cirrhosis. It is given together with another drug called Sovaldi (sofosbuvir).
4. How To Take Natdac 30mg Tablet?
Daclatasvir is available in 30 and 60mg tablets, and the usual dose is 60mg once daily with or without food. It must be used in combination with other hepatitis C medications and is not effective if taken alone. Treatment should be managed by a doctor who has experience treating hepatitis C. People with HCV genotypes 1 or 4 who are being treated for the first time and do not have liver cirrhosis should take daclatasvir plus sofosbuvir for 12 weeks. Due to limited clinical trial data, there is still uncertainty about the best way to treat people with genotypes 2, 3 or 4.
5. Drug interaction of Natdac 30mg
Serious drug interactions can occur when certain medicines are used together with daclatasvir. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
6. Side Effects of Natdac 30mg
- nausea, or diarrhea may occur.
- severe dizziness,
- trouble breathing.
7. Warning And Precaution of Natdac 30mg tablet
You should not use Natdac if you are allergic to daclatasvir. If you take daclatasvir with sofosbuvir, there may be other reasons you should not take this combination treatment. Tell your doctor about all your medical conditions.
Some medicines can interact with Natdac and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs: rifampin, carbamazepine, phenytoin.
To make sure Natdac is safe for you, tell your doctor if you have:
- liver problems other than hepatitis C;
- heart disease;
- if you also use amiodarone (a heart rhythm medicine); or
- if you have received a liver transplant.
It is not known whether Natdac will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether daclatasvir passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Natdac is not approved for use by anyone younger than 18 years old
8. Uses of Natdac 30mg
Natdac (Daclatasvir) is used to treat chronic hepatitis C infections (genotype 1, 3 and 4) in adults with uncomplicated liver disease whose liver is still functioning correctly (compensated liver disease).
It may be used in people who have not yet received treatment for their hepatitis C, or for people whose disease has not improved with previous treatment.
It may be used in combination with sofosbuvir (Sovaldi), either with or without ribavirin (Rebetol), or with ribavirin plus peginterferon alfa (ViraferonPeg or Pegasys).
9. Storage of Natdac 30mg
Store at 25°C (77°F); excursions permitted between 15°C and 30°C (59°F and 86°F).